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The antioxidant properties of medicinal plants have been shown to inhibit ROS and RNS formation as well as apoptosis, suggesting that these plants could serve as effective complementary therapies to mitigate the adverse effects of commonly used ototoxic medications (Mahmoudian-Sani et al

doi: 10.3389/fbioe.2024.1526612 Received 12 November 2024 Accepted 17 December 2024 Published 08 January 2025 Volume 12 - 2024 Edited by Teruyoshi Sasayama, Kyushu University, Japan Reviewed by Regina Tavano, University of Padua, Italy Rakesh A

[DOI] [PMC free article] [PubMed] [Google Scholar] Hovda K.E., Guo C., Austin R., McMartin K.E

[5] [6] Glycine (along with cysteine and glutamic acid) is a true substrate for glutathione synthesis

To the best of our knowledge, genistein has not shown any clinical evidence of an anticancer effect on human CNS cancers [165]